Multifocal Anaplastic Pancreatic Carcinoma Requiring Neoadjuvant Chemotherapy and Total Pancreatectomy: Report of a Case

Authors

  • Teresa S Jones Section of GI, Tumor and Endocrine Surgery, Department of Surgery, University of Colorado at Denver. Aurora, CO, USA
  • Edward L Jones Section of GI, Tumor and Endocrine Surgery, Department of Surgery, University of Colorado at Denver. Aurora, CO, USA
  • Martine McManus Division of Gastrointestinal Pathology, Department of Pathology, University of Colorado at Denver. Aurora, CO, USA
  • Raj Shah Division of Gastroenterology and Hepatology, Department of Medicine, University of Colorado at Denver. Aurora, CO, USA
  • Csaba Gajdos Section of GI, Tumor and Endocrine Surgery, Department of Surgery, University of Colorado at Denver. Aurora, CO, USA

DOI:

https://doi.org/10.6092/1590-8577/1416

Keywords:

Carcinoma, Neoadjuvant Therapy, Pancreatic Neoplasms

Abstract

Context Anaplastic pancreatic carcinoma is a rare tumor with poor survival. Data on surgical and medical therapies are currently limited to case reports and case series with small numbers. Case report We describe a case of multifocal anaplastic pancreatic carcinoma treated with neoadjuvant FOLFIRINOX (oxaliplatin, irinotecan, fluorouracil and leucovorin) and total pancreatectomy with subsequent patient disease-free survival currently at 12 months. Discussion The goal for anaplastic pancreatic carcinoma treatment should continue to be complete surgical resection. Optimum chemotherapeutic options continue to be investigated.

Image: Foreign body giant cells.

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References

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Foreign body giant cells

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Published

2013-05-10

How to Cite

Jones, T. S., Jones, E. L., McManus, M., Shah, R., & Gajdos, C. (2013). Multifocal Anaplastic Pancreatic Carcinoma Requiring Neoadjuvant Chemotherapy and Total Pancreatectomy: Report of a Case. JOP. Journal of the Pancreas, 14(3), 289–291. https://doi.org/10.6092/1590-8577/1416

Issue

Vol. 14 No. 3 (2013): May - p. 221-303

Section

CASE REPORTS

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